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CH3041
METALLOTHIONEN
• Metallothionen
is a small -SH rich protein which binds to Pb, Hg strongly
(Mn+-S bonds) to detoxify the system.
(Mn+-S bonds) to detoxify the system.
• The metal is complexed by metallothionen and
then eliminated in the urine.
• This mechanism works for low level chronic exposure but
once the effect of this
detoxifying protein is
saturated the excess
TM will concentrate in
the body.
once the effect of this
detoxifying protein is
saturated the excess
TM will concentrate in
the body.
