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CH3041
PARATHION vs MALATHION
Structure and Function. 
Synthetic chemists and
computational chemists work together to design more effective and less toxic OPs.
hydrolysis sites
• Malathion (Maldison ) is hydrolysed by enzymes
in mammals but not insects. This means that
it has comparable effect to parathion but
with a LD50 11000.
t½ 100d soil
       fish kills
Chlorpyrifos
Malathion
Parathion
GCMS chlorpyrifos, malathion