L1
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13
CH3041
PARATHION vs MALATHION
Structure and Function
.
Synthetic chemists and
computational chemists work together to
design more effective and less toxic OPs.
hydrolysis sites
•
Malathion
(
Maldison
)
is hydrolysed by enzymes
in mammals but not insects. This means that
it has comparable effect to parathion but
with a
LD
50
11000
.
t½ 100d soil
fish kills
Chlorpyrifos
Malathion
Parathion
GCMS chlorpyrifos, malathion