L1 /
6
CH3041
MODE OF ACTION
• The toxicant is
often
modified in the kinetic
phase to produce
metabolites which may
be more or less active
than the toxicant.
modified in the kinetic
phase to produce
metabolites which may
be more or less active
than the toxicant.
• If a toxicant
acts as a systemic poison it
will usually interact with a receptor resulting
in a modified receptor which produces a
biochemical effect eg. enzyme inhibition
will usually interact with a receptor resulting
in a modified receptor which produces a
biochemical effect eg. enzyme inhibition
• Following this
there are physiological
effects and /or behavioural effects.
eg. CNS convulsions
effects and /or behavioural effects.
eg. CNS convulsions
