L1 /
15
CH3041
MATC,NOAEL,ADI,TLV,STEL
• The NOAEL is the No Observed Adverse
Effect Level for a substance which is the
dose where the body can dispose of the
chemical safely – not the threshold level.
Effect Level for a substance which is the
dose where the body can dispose of the
chemical safely – not the threshold level.
• LOAEL lowest observed
adverse effect level
• Maximum Acceptable Toxic Concentration
MATC = (NOAEL + LOAEL) / 2
- this is around the threshold value
MATC = (NOAEL + LOAEL) / 2
- this is around the threshold value
• With an estimate of exposure (area, conc., duratn, frequency, input rate, total exp. time)
& the MATC it is possible to estimate the:
ADI (Average Daily Intake) and the
ADI (Average Daily Intake) and the
TLV (Threshold Limit Value) of the toxicant.
STEL
(Short Term Exposure Limit). The maximum
concentration that employees can be exposed to over a
specific time period (15 min) no more than 4
times per day.
