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CH3041
ACUTE TOXICITY
BIOASSAY
• A homogeneous
population under good
conditions is dosed with
the chemical at carefully
regulated concs.
Usually for 48 or 96h.
population under good
conditions is dosed with
the chemical at carefully
regulated concs.
Usually for 48 or 96h.
• The threshold is the
dose above which some
response is observed
in the organisms. The LD50 is the dose that results in mortality of 50% of the population.
dose above which some
response is observed
in the organisms. The LD50 is the dose that results in mortality of 50% of the population.
• The concentration
of toxicant that results
in an LD50 is referred to as an LC50.
in an LD50 is referred to as an LC50.
(death)
log(dose)
