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CH3041
DOSE RESPONSE
CURVES
• A dose is the amount
of chemical applied
per unit body mass.
eg. mg / kg
of chemical applied
per unit body mass.
eg. mg / kg
• Response is the effect
on the organism.
eg. death.
on the organism.
eg. death.
• Intuitively one would
expect a linear type
of response from the
organism but this is not observed instead
there is often a “classic” S - type curve
as the dose is increased.
expect a linear type
of response from the
organism but this is not observed instead
there is often a “classic” S - type curve
as the dose is increased.
N.B. Normally dose is
presented on a log scale
presented on a log scale
