Type
Time Area
1) Acute local 1s- 24h
skin, eyes, mm’s
2) Chronic local
1d- 10y skin, eyes, mm’s
3) Acute systemic
1s - 24h inhalatn, ingestn
remote organs
4) Chronic systemic 1d
- 10y inhalatn,ingestn
remote
organs
• Usually an acute exposure will be a
single
dose of the chemical.
•To find the response of an organism to
a toxicant dose-response curves are used.