L1 /   
1
CH3041
ON-LINE LECTURE 20
CALIBRATION
• Continuing Calibration Standard (CCS) is
run at the beginning and end of analysis and
every 10 samples in between. Contains the
analyte of interest made up from calibration standards of known concentration.
• Calibration Verification Standard (CVS).
A commercial QC standard run at the beginning and end of analysis.
• Calibration blank: analyte-free matrix.
External calibration
• Calibration curve: the instrument response
is plotted versus concentration of analyte.
Typically 5 concentrations (increasing) are run spanning the concentration of interest.
• Used in colorimetry.