CH1012
                                         L1 /   
‹#›
                                         L1 /   
16
DRUG DESIGN
A large number of new drugs contain substituted aromatic rings.
•Design of such drugs relies on substitution of the correct substituent at the correct site.
• Without the rules for EAS reactions we have learnt(!) it would not be possible to synthesize drugs such as methotrexate, an antileukemic drug, in reasonable yields.