L1 /
11
CH1012
SN2
REACTIVITY
The SN2 reaction
rate is sensitive to steric hindrance
at the reaction centre.
RCH2-X > R2CH-X >> R3CX
1o 2o 3o
Decreasing rate
Increasing
steric hindrance
Once we arrive at the 3o haloalkanes the
steric hindrance is so great that the second
mechanism SN1 becomes the preferred
route.
steric hindrance is so great that the second
mechanism SN1 becomes the preferred
route.
