L1 /
14
CH1012
MULTIPLE
SUBSTITUTION
The aromatic ring may be activated by substitution towards further substitution.
• Substituents such
as -OH and -NH2 are able to activate the ring to substitution and bromine (without the Lewis acid catalyst) is able to multiply
substitute the
aromatic ring.
substitute the
aromatic ring.
aniline 2,4,6-tribromoaniline
