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CH1012
D2O
EXCHANGE
Deuterium (D) is an isotope (1p, 1n) of hydrogen with a different spin value (I = 1).
• D may be used when we want to substitute an H atom in a molecule & then observe the absence of the H signal in a NMR spectrum.
• D2O is the deutero
analogue of H2O and it may be used to identify OH & NH protons in an NMR spectrum.
the R-O-H signal “disappears”
• CDCl3 is the deutero analogue of CHCl3.
Again the 2D of the solvent is not observed
when we are measuring 1H NMR spectra.
Again the 2D of the solvent is not observed
when we are measuring 1H NMR spectra.
